Genomic Biomarker Analysis by QPCR & Droplet Digital PCR
Genomic Biomarker Analysis by QPCR & Droplet Digital PCR
Whether your pipeline requires extreme high-throughput screening or absolute single-molecule quantification, our dual-platform approach ensures you have the right genomic tool for every stage of your therapeutic development
Immune Repertoire Profiling (TCR/BCR-Seq):
Next-generation sequencing and RT-PCR of T-cell (and B-cell) receptors to track clonal expansion, diversity (CDR3 region), and antigen specificity across human, NHP, and rodent models.
Cross-Species Assay Design:
Species-specific and universal primers/probes for absolute quantification (ddPCR, qPCR) of target genes and transcripts.
Vector Biodistribution & Copy Number (VCN):
Curve-free, ultra-sensitive tracking of cell therapy persistence and gene vector localization across preclinical animal organ panels.
Micro-Chimerism & Engraftment:
Quantify human cell engraftment levels in immunocompromised/humanized rodent models.
High-Throughput Profiling:
Supports extensive gene expression analysis, as well as comprehensive microRNA and noncoding RNA profiling.
Cancer Biomarkers & Rare Mutations:
Detects rare DNA target copies and resolves varying degrees of cancer mutations with superior sensitivity.
Biologics Safety & Contaminant Testing:
GMP-ready applications for detecting residual host cell DNA (e.g., HEK293) and absolute quantification of mycoplasma to ensure product safety.
