Translational & Clinical Research
Accelerating the Continuum from Preclinical Discovery to Clinical Proof-of-Concept
ImmunitasBio provides end-to-end, high-complexity translational, bioanalytical, pathology, and immunomonitoring services to biotechnology and pharmaceutical innovators worldwide. Combining specialized technical platforms with rigorous regulatory alignment (GLP/GCLP compliance), we provide actionable, mechanism-reflective data to de-risk candidate therapeutics, substantiate safety profiles, and validate clinical efficacy.
Integrated Modality Solutions
Therapeutic Modality |
Primary Translational Challenges Addressed |
Core Service Packages |
Immuno-Oncology |
TME immunosuppression, target engagement, CRS toxicity, durable response monitoring. |
High-parameter flow cytometry, multiplex IHC spatial mapping, Incucyte live-cell tumor killing, ELISPOT, soluble cytokine panels. |
Biologics & Bispecifics |
Immunogenicity (ADA/NAb), off-target cross-reactivity, effector function validation. |
Multi-tiered ADA & cell-based NAb assays, GLP-aligned TCR IHC, PK/PD assays, MOA-reflective potency testing (ADCC/CDC). |
Cell & Gene Therapy (CGT) |
In vivo persistence, vector biodistribution, VCN quantification, target tissue expression. Immunogenicity (ADA/NAb). |
dPCR VCN and biodistribution, RNAscope ISH, MHC multimer flow tracking, transgene IHC, standardized PBMC cryopreservation. Multi-tiered ADA & cell-based NAb assays. |
Peptide & Oligo Therapies |
Rapid metabolic clearance, immunogenicity risks of generic/novel peptides, receptor binding. |
High-sensitivity bioanalysis, peptide immunogenicity risk profiling, MHC binding/competition assays, target receptor localization IHC. |
Vaccines |
Cellular immunogenicity & memory profiling, humoral efficacy & neutralizing antibody generation, long-term durability, reactogenicity, and vector biodistribution. |
T-cell & B-cell ELISPOT, bespoke ELISA for Ig titers, cell-based NAb assays, high-parameter flow cytometry for polyfunctional profiling, AIM assay, Luminex cytokine panels, and ddPCR biodistribution. |
